Diisocyanate mediated polyether modified gelatin drug carrier for controlled release
نویسندگان
چکیده
منابع مشابه
Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation
A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...
متن کاملGelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation
A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...
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Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
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In this paper, the synthesis of new montmorillonite nanocomposite hydrogel (MMTNH) based on poly (acrylic acid-co-acrylamide) grafted onto starch, is described. Montmorillonite (MMT) as nanometer base, acrylic acid (AA) and acrylamide (AAm) as monomers, ammonium persulfate (APS) as an initiator, N,N-methylenebisacrylamide (MBA) as a crosslinker and starch as a biocompatible polymer were pre...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2014
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2013.01.005